Samuel Henderson Seals was born about 1840 in Georgia. He married (1) Sarah Mackle about 1865 in Cass, IL. He then married (2) Sarah Eastwood on February 22, 1874 in Cass, IL. She was the daughter of George Eastwood and Caroline Etherton.

Samuel and Sarah Mackle had two children. First born was Franklin Seals born about 1866. George Seals was born about 1873. Samuel and Sarah Eastwood also had two children. Sarah Caroline Seals was born about 1874 in IL. and Samuel Sylvester Seals was born February 23, 1878 in Ullin. He died April 15, 1927 in Ullin.