Isabel, an incorporated town in Barber county, is located on the Atchison, Topeka, & Santa Fe R. R. 13 miles north of Medicine Lodge, the county seat. It has a bank, a weekly newspaper (the Herald), over a score of mercantile establishments, express and telegraph offices, and a money order postoffice with one rural route. The population in 1910 was 222.
(Kansas: A Cyclopedia of State History, Embracing Events, Institutions, 1912, edited by Frank Wilson Blackmar, Vol. 1, page 944)
Isabel was founded in 1887. Isabel was named for the daughter of a surveyor.
(Source: Wikipedia, the free encyclopedia)